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CONFERENCE SERIES: Biomarkers and Diagnostics

Recorded at: Next Generation Dx Summit

Digital Course: Applications of Detection Theory in Diagnostics


Order DVD2011 SC4 DVD Cover About this Product: 

This digital course defines false positives, false negatives and dichotomous test as well as sensitivity, specificity, limit-of-detection, and response time. Attendees will understand and analyze a dose-response curve, construct and analyze a Receiver Operating Characteristic (ROC) curve from raw data, define Positive Predictive Value (PPV) and Negative Predictive Value (NPV), and interpret detector performance trade-offs using a ROC curve. 




About this Product:
2 Presentations
83 Slides
Over 161 Minutes
Individual: $345
Site License: $1380

Agenda At A Glance: 

Applications of Detection Theory in Diagnostics

  • The Dichotomous Test
  • Analysis and Definition of FP, FN, CP, CN
  • Definition of Sensitivity, Specificity, and LOD
  • Construction of the Receiver Operating Characteristic
  • ROC Curve Trends and Interpretation
  • Negative and Positive Predictive Values
  • Detection Theory and Measurements
  • Applications of ROC Curves in Sensing
  • Applications of ROC Curves in Diagnostics
  • Perform Cost-Benefit Analysis
  • Principles of Decision Tree Analysis
  • Constructing and Interpreting a Decision Tree
  • Practical Applications of Decision Tree Analysis
  • The “Spider” Chart and Systems Level Analysis

John CarranoInstructor: John C. Carrano, Ph.D., President, Carrano Consulting, LLC

Biography: John Carrano is President of Carrano Consulting, LLC. Previously, he was the Vice President, Research & Development, Corporate Executive Officer, and Chairman of the Scientific Advisory Board for Luminex Corporation, where he led the successful development of several major new products from early conception to market release and FDA clearance. Before joining Luminex, Dr. Carrano was as a Program Manager at DARPA, where he created and led several major programs related to bio/chem sensing, hyperspectral imaging and laser systems. Dr. Carrano is a West Point graduate, and holds a doctorate in Electrical Engineering from the University of Texas at Austin. He has co-authored over 60 scholarly publications and has 3 patents pending. He is an SPIE Fellow.

About the Conference: 

The Next Generation Dx Summit (Enabling Point-of-Care Diagnostics, Emerging Molecular Markers of Cancer, Molecular Diagnostics for Infectious Disease, Companion Diagnostics, Commercialization of Molecular Diagnostics, Translating Proteomics & Metabolomics into the Clinical Laboratory, and Mass Spectrometry in Clinical Diagnostics) is designed to bring together all of the major players in the evolving areas of diagnostics.  This year, we are introducing proteomic and metabolomic technologies that are making their way into clinical diagnostics. We have assembled an impressive faculty of speakers from industry, government, and leading academic institutions. This meeting will showcase improvements in technology research and development with an emphasis towards application to the clinical laboratory and commercialization. Plan to hear what the key players in the industry are saying about what to expect for the rapid changes ahead.

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