Diagnostics is a more-than-$50-billion industry with a critical role in medicine, especially in today’s world of personalized medicine. Numerous new technologies in development stand to revolutionize the diagnostics world. Realizing this is an area that is ripe for disruption, the 2018 Business Stream at Next Generation Dx Summit will foster development and collaboration among technology developers, pharmaceutical executives, payers and investors. The programs will bring together translational scientists, clinicians, business experts, payers, regulators and investors to discuss and solve the critical challenge of market access strategies, partnering, commercialization, coverage and reimbursement for diagnostic technologies.