2018 Podcasts

Challenges and Opportunities in Molecular Testing for Infectious Disease

Jennifer Dien Bard, PhD, D(ABMM), Director, Microbiology and Virology, Children’s Hospital Los Angeles; Associate Professor, Pathology and Laboratory Medicine, Keck School of Medicine, University of Southern California

Dr. Jennifer Dien Bard shares her insights into what the biggest challenges and opportunities are in implementing molecular point-of-care testing for infectious disease diagnostics, and rapid genetic and phenotypic susceptibility testing. Jennifer will be speaking at Molecular Diagnostics for Infectious Disease and co-instructing a short course on Rapid Diagnostics for Antimicrobial Resistance at the Next Generation Dx Summit August 20 to 24, 2018 in Washington, DC.

Dissecting Liquid Biopsy in MBC: CTCs, ctDNA and CAMLs to Evaluate Innate Immunity

Massimo Cristofanilli, MD, FACP, Professor, Medicine; Associate Director, Translational Research and Precision Medicine; Director, OncoSET Precision Medicine Program, Medicine-Hematology and Oncology, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University

Prof. Massimo Cristofanilli shares his perspective on the future of liquid biopsy, the complementary purposes of CTC and cfDNA technologies, and when one should expect clinical utility of liquid biopsies.

Last Mile of Molecular Diagnostics in Precision Medicine and Healthcare

Bruce Quinn, MD, PhD, Principal, Bruce Quinn Associates

Dr. Bruce Quinn talks about his latest work, challenges to implementing precision medicine, advice for overcoming them and tips for integrating into the clinic. He discusses exciting new developments that are emerging and where the field is heading.

Rapid Fire: Getting to Know Suman Bose

Suman Bose, PhD, Postdoctoral Fellow, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology

Suman Bose of Massachusetts Institute of Technology speaks to CHI on May 3, 2018. Dr. Bose will be speaking at the Single Cell Analysis and at the Microfluidics and Lab-on-a-Chip Devises for point of care testing tracks at the upcoming Next Generation Diagnostics Summit that is held from August 20th through the 24th in Washington, D.C.

Looking at the Value of NGS-based Diagnostic Testing for Lung Cancer Patients

Daryl Pritchard, PhD, Professor, Bioengineering, University of Washington

Daryl Pritchard of PMC speaks to CHI on May 4th, 2018. Darryl will be speaking at a shared session between the Coverage and Reimbursement for Advanced Diagnostics Track and the Precision Medicine tracks at the upcoming Next-Generation Diagnostic Summit that is held from August 20th to the 24th in Washington, D.C.

Developing Low Cost Diagnostics for Infectious Disease – Strategies and Advice

Paul Yager, PhD, Professor, Bioengineering, University of Washington

Paul Yager of University of Washington speaks to CHI on May 4, 2018. Dr. Paul Yager from the University of Washington. Dr. Yager will be speaking at the Enabling Point-of-Care Diagnostics and the Microfluidics and Lab-on-a-Chip Devices for point-of-care testing tracks at the upcoming Next Generation Diagnostic Summit that is held from August 20th to the 24th in Washington, DC.


2017 Podcasts

 

Wild West: Exome Sequencing in the Clinic

Avni B. Santani, Ph.D., Assistant Professor, Clinical Pathology, University of Pennsylvania School of Medicine; Scientific Director, Molecular Genetics Laboratory, The Children’s Hospital of Philadelphia

Avni Santani of CHOP speaks to CHI on Tuesday August 1st, 2018. Dr. Santani will be speaking during the Clinical NGS Assays: Applications and Interpretation meeting at the Next Generation Diangostics SummitAugust 15-18, in Washington DC.

The Role of Molecular Diagnostics in Antibiotics Stewardships Programs

Elena Grigorenko, Vice President, Research and Development, Diatherix, Eurofins Clinical Diagnostics, LLC

Dr. Elena Grigorenko of Diatherix, speaks to CHI on Wed. July 19, 2017. Dr. Grigorenko will be speaking during the Molecular Diagnostics for Infectious Disease Conference August 16-17, 2017 at the Grand Hyatt Washington in Washington, DC

Point-of-Care Devices in Liquid Biopsy

Andrew H. Ko, M.D., Professor, Clinical Medicine, Division of Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco

Andrew Ko from UCSF recently spoke with CHI about his collaboration with Two Pore Guys, and the innovations they are implementing using point-of-care devices in liquid biopsy. He will be speaking at the Next-Generation Dx Summit in the Enabling Point-of-Care Diagnostics conference on August 15. Dr. Ko is working with Two Pore Guys advancing technology to enable cancer patients to monitor their progress from home.

Point-of-Care Devices in Immunotherapy and Beyond

M. Allen Northrup, Ph.D., FRSC, CEO, MIODx

Dr. Allen Northrup from MIODx recently spoke with CHI about the future applications of point-of-care in treating cancer. He will be speaking at the Next-Generation Dx Summit in the Enabling Point-of-Care Diagnostics conference on August 15. He is working on developments to predict and monitor patients’ responses to immunotherapy.

The Microbiome’s Diagnostic Potential in Infectious Disease Point-of-Care Assays

Georgios Kitsios, M.D., Ph.D., Instructor of Medicine; Post-Doctoral Scholar, Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Medical Center

Georgios Kitsios of the University of Pittsburgh Medical Center spoke to CHI to discuss his latest research in rapid microbiome-based diagnostics of infectious disease and how he sees the microbiome filling a need in point-of-care diagnostics for infectious disease. He also discusses the epidemic of antibiotic resistance and how this has shaped his research in the critical care space, as well as the biggest challenges he and other scientists face in this field.

NGS in DNA Forensics: Benefits, Challenges, and Future Potential

Cassandra D. Calloway, Ph.D., Assistant Scientist and DNA Program Coordinator, Genetics and Genomics and Forensic Graduate Program, Children’s Hospital Oakland Research Institute and University of California, Davis

Cassandra Calloway of Children’s Hospital Oakland Research Institute and the Universities of California at Davis and San Francisco spoke to CHI to discuss how next generation sequencing, or massively parallel sequencing, is different from current methods used in DNA forensics. She discusses the benefits of this new technology and its potential for benefitting all forensics labs.

A Multiplexed Approach for Predicting Responses to Cancer Immunotherapy: Implementation and Challenges

Robert A. Anders, M.D., Ph.D., Associate Professor of Pathology, Division of GI and Liver Pathology, Bloomberg-Kimmel Institute for Cancer Immune Therapy, Johns Hopkins Medicine

Robert Anders of Johns Hopkins Medicine speaks to CHI on May 16th, 2017. Dr. Anders will be speaking during the Biomarkers for Cancer Immunotherapy and Combinations meeting at the Next Generation Diagnostics Summit August 15-18th in Washington DC.

Geisinger’s Strategy for Clinical NGS Implementation

Marc S. Williams, M.D., FAAP, FACMG, FACMI, Director, Genomic Medicine Institute, Geisinger Health System

Marc Williams of Geisinger Health System speaks to CHI on May 19th, 2017. Dr. Williams will be speaking during the Clinical NGS Assays: Applications and Interpretation meeting at the Next Generation Diagnostic Summit, August 15th to the 18th in Washington D.C.

Precision Medicine Outside of Oncology

Jonathan Pan, Ph.D., MBA, Vice President, Head of Biomarker Strategy and Development, Aevi Genomic Medicine, Inc.

Jonathan Pan of Aevi Genomic Medicine speaks to CHI on May 15th, 2017. Dr. Pan will be speaking during the Companion Diagnostics: Strategy and Partnerships meeting at the Next Generation Diagnostic Summit, August 15th to the 18th in Washington D.C.

Implementing Point-of-Care Testing and Pharmacogenetic Testing in the Community Pharmacy

Edana Holliday, PharmD, Clinical Pharmacist, Community Ambulatory Care Services, Rx Clinic Pharmacy; VP, Communications, Pharmacogenetics Center of Excellence

In this podcast from CHI on May 18th, Edana Holliday speaks about how Rx Clinic Pharmacy is working to integrate point-of-care testing and pharmacogenetic testing into their practice, and how use of these methods can bring doctors and pharmacists into new collaborations. To see her in person, check out the Pharmacy-Based Point-of-Care Testing conference, part of the Next Generation Diagnostics Summit, August 15-18th in Washington DC.

Genome Sequencing Clinical Applications: What Will it Take to Make NGS Standard of Care?

Liz Worthey, Ph.D., Faculty Investigator, Director, Software Development and Informatics, HudsonAlpha Institute for Biotechnology

In this podcast from CHI, on May 11th, 2017 Liz Worthey, Faculty Investigator and Director at HudsonAlpha Institute for Biotechnology sat down to discuss her work in whole genome sequencing to diagnose and monitor rare diseases. She discusses her team’s work with standardizing NGS tests, utilizing sequencing as a diagnostic test, and challenges to making whole genome sequencing standard of care in clinical practice.

Reimbursement of Companion Diagnostics: Discussions for Precision Medicine

Omar Perez, Ph.D., RAC, Director and Diagnostics Lead, Oncology Programs, Worldwide R&D, Pfizer Inc.

Omar Perez of Pfizer speaks to CHI on May 10, 2017. Dr. March will be speaking during the Companion Diagnostics: Strategy & Partnerships meeting at the Next Generation Diagnostics Summit, August 15-18th in Washington DC.

Walking Down Evidence Street™: Where the Market Meets Evidence

Suzanne Belinson, Ph.D., Executive Director of Clinical Markets, Blue Cross Blue Shield Association

Keynote speaker Suzanne Belinson of Blue Cross Blue Shield Association speaks to CHI on May 9, 2017. Dr. Belinson will be speaking during the Coverage and Reimbursement of Advanced Diagnostics meeting at the Next Generation Diagnostics Summit, August 15-18th in Washington DC.


2016 Podcasts

Combining Whole Genome Sequencing with Clinical Care

with David Bick, M.D., CMO & Faculty Investigator, HudsonAlpha Institute for Biotechnology; Founder & CMO, Envision Genomics; Medical Director, Smith Family Clinic for Genomic Medicine

David Bick of HudsonAlpha speaks to CHI on July 20th, 2016. Dr. Bick will be speaking during the Health and Wellness Genomic Screening symposium at the Next Generation Diagnostics Summit, August 23-26th, in Washington DC.

Transitioning Basic Research Into Actual Diagnostics: A Preview

Timothy D. Minogue, Ph.D., Chief, Molecular Diagnostics Department, Diagnostic Systems Division, USAMRIID

Tim Minogue of the United States Army Medical Research Institute for Infectious Diseases speaks to CII on July 8, 2016. Tim Minogue will be speaking during the Molecular Diagnostics for Infectious Disease track at the Next Generation Diagnostics Summit, August 24th, in Washington DC.

Digital PCR: Changing the Way Scientists Conduct Research

Hatim Husain, M.D., Assistant Professor, Medicine, Hematology and Oncology, University of California, San Diego

Dr. Hatim Husain, Assistant Professor of Medicine in the department of Hematology and Oncology at UCSD spoke to CHI to discuss how using digital PCR has changed the way he conducts his research in oncology. He describes some of the benefits and challenges of integrating digital PCR into a laboratory, as well as discusses what he’s looking forward to seeing at the Digital PCR symposium.

Medicine for the Future: NGS Pricing and Precision Medicine Implementation in the Clinic

Jamie Platt, Ph.D., MB(ASCP), Managing Director, BRIDGenomics, LLC.

Jamie Platt of BRIDGenomics speaks to CHI on June 22, 2016. Dr. Platt will be speaking during the Health and Wellness Genomic Screening Symposium at the Next Generation Diagnostics Summit, August 23-36, in Washington DC.

The Microbiome and Human Reproduction: Current Research and Future Developments

Jason Franasiak, M.D., FACOG, Attending Physician, Reproductive Medicine Associates of New Jersey

Dr. Jason Franasiak, Attending Physician at the Reproductive Medicine Associates of New Jersey, spoke to CHI to discuss the origins of germ theory and human microbiome research, specifically as it relates to human reproduction. He'll detail some of his research on the uteran microbiome during embryo implantation, future developments for diagnostics, and how other scientists may utilize his research and apply it to their own studies.

Blood-Based Genotyping of Colorectal Cancer Patients

Giulia Siravegna, University of Torino and the IRCCS-Candiolo Cancer Institute

Giulia Siravegna of the University of Torino and the IRCCS-Candiolo Cancer Institute discusses the recent study on the potential of circulating tumor DNA (ctDNA) to evaluate response to chemotherapy in colorectal cancer patients; how ctDNA will be used in conjunction with other tests in the standard of care for colorectal cancer; exciting applications emerging for liquid biopsies; and results from the recent liquid biopsy study published in Nature.


2015 Podcasts

Metabolomics for Infectious Disease: A Focus on Sepsis

Raymond J. Langley, Ph.D., Associate Research Scientist, Lovelace Respiratory Research Institute

CHI chats with Raymond J. Langley, Ph.D., Associate Research Scientist, Lovelace Respiratory Research Institute. Dr. Langley discusses his current work on metabolomics risk analysis models for sepsis as well as the challenges associated with them and other developing technology.

Biomarkers for Infectious Disease: Current Challenges and Advancements

Kate Simon, Ph.D., Senior Consultant, Biologics Consulting Group, Inc.

CHI chats with Kate Simon, Ph.D., Senior Consultant at Biologics Consulting Group, Incorporated. Dr. Simon discusses reference methods for new biomarkers of infectious diseases, how to establish reference methods, and the biggest challenges scientists are facing in this field in 2015 and beyond.

Technological Advancements for Diagnostics Sequencing

Reiner Babiel, Ph.D., Executive Director, Consulting, RBDC

CHI chats with Reiner Babiel, Ph.D., who is the Executive Director of Consulting at RBDC. Dr. Babiel discusses NGS in infectious disease diagnostics, key advancements in the field, and the upcoming Next-Generation Diagnostics Summit.

POC in the Pharmacy: Practical, Legal, and Future Perspectives

Allison M. Dering-Anderson, BA, Pharm.D., RP, FAAIM, Clinical Assistant Professor, Pharmacy, University of Nebraska College of Pharmacy

CHI chats with Ally Dering-Anderson, BA, Pharm.D., RP, FAAIM, who is a Clinical Assistant Professor of Pharmacy at the University of Nebraska College of Pharmacy. Ally discusses legal considerations, collaborative care agreements, training, and the changing role of pharmacies.

Point-of-Care Testing in a Retail Health Clinic Setting

Alexander Sbordone, J.D., Operations Manager, MinuteClinic, CVS Caremark Corporation

CHI's Samantha Lewis speaks with Daniel Kerls, director of ambulatory operations at CVS' Minute Clinic, as well as Alexander Sbordone, who is the Minute Clinic operations manager at CVS. Kerls and Sbordone discuss staffing MinuteClinic, the types of diagnostic tests they seek out, and the future direction of rapid clinics.


2014 Podcasts

Preview of the Panel Discussion on IMPLEMENTATION OF MOLECULAR TESTING: Demonstrating Clinical Utility and Measuring Health Outcomes

Panel of speakers moderated by Julie Lynch, Ph.D., featuring Michael Kelly, M.D., Vickie L. Venne, Donna Polizio and John W. Hanna

The panelists describe what they will be covering during the panel discussion, which include third party payer requirements for clinical utility and funding sources. They will also review how the higher level of evidence will impact implementation, equity and access.

Companion Diagnostics – Regulatory Improvements, Market Trends and Emerging Technologies

Richard A. White, Ph.D., Director, Global Strategy, Breast and Colon Products, Genomic Health, Inc.

Amid Zand interviews Dr. Richard White of Genomic Health on June 11, 2014. Dr. White will be speaking at the Companion Diagnostics: Technology and Reimbursement track at the Next Generation Dx Summit, August 19-21, in Washington, D.C.

Single-Cell Sequencing and Complex Cancer Genome Analysis for Clinical Parameters and Personalized Therapy

James Hicks, Ph.D., Research Professor, Cancer Genomics, Cold Spring Harbor Laboratory

An-Dinh Nguyen interviews James Hicks of Cold Spring Harbor Laboratory on June 24, 2014. Dr. Hicks will be a speaker at the Single-Cell Sequencing conference, part of the Next-Generation Dx Summit, August 19-21 in Washington, DC.

Incidental Findings, Unwanted Information, and the “Safety” of Genomic Testing

Kimberly Strong, Ph.D., Assistant Professor and Primary Faculty, Program in Genomics and Ethics, Institute for Health and Society - Center for Bioethics and Medical Humanities & Human and Molecular Genetics Center, Medical College of Wisconsin

Dr. Kimberly Strong of the Medical College of Wisconsin speaks to CHI about patient attitudes towards receiving genomic information, access to information, and the future of genomic medicine. Dr. Strong will be speaking at Cambridge Healthtech Institute’s Inaugural Inherited Disease Diagnostics Conference, taking place August 19-20, 2014 in Washington, DC as part of the Next Generation Dx Summit.

Single-Cell Genomic Sequencing: Improvements, Challenges and Utility

Jan Vijg, Ph.D., Professor and Chairman, Genetics, Albert Einstein College of Medicine

An-Dinh Nguyen interviews Jan Vijg of Albert Einstein College of Medicine on June 12, 2014. Dr. Vijg will be a featured speaker at the Single-Cell Sequencing conference, part of the Next-Generation Dx Summit, August 19-21 in Washington, DC.

Integration of Genomics into Medical Practice: Educational Challenges

Bruce Korf, M.D., Ph.D., Wayne H. and Sara Crews Finley Chair, Medical Genetics; Professor and Chair, Genetics; Director, Heflin Center for Genomic Sciences, University of Alabama at Birmingham

Dr. Bruce Korf of the University of Alabama at Birmingham speaks to CHI about some of the educational challenges in genomic medicine implementation, the educational needs of physicians, and how he sees genomics being used clinically. Dr. Korf will be speaking at Cambridge Healthtech Institute’s Inaugural Inherited Disease Diagnostics Conference, taking place August 19-20, 2014 in Washington, DC as part of the Next Generation Dx Summit.